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Market Assessment and Forecast: New Formulation Launch Value

Client Situation

  • Client was planning to launch a new formulation (SC) of already approved RA biologic (IV formulation) that was available in the market for over 5 years with:

    Long term safety data

    Physical familiarity with molecule

  • There were few challenges such as the difficulty in assessing potential cannibalization, highly competitive marketspace, complexity in forecasting by Payers.
  • Client reached out to Digtinctive to provide a framework for forecast modelling and estimating potential value of new formulation.

Objective

Develop an in-depth RA market forecast assessing the following:

Market growth

Peak product demand

Patient vs. TRx update

Cannibalization assessment

Sensitivity analysis

Branded competition

Approach/Solution

A unified analytics framework was developed to address client needs, which included:

  • Forecasting Triangulation:

    Patient-based forecast (based on patient claims data) model, focusing on:

    New Patient Starts & Switches

    Future market events impact

    Days on Therapy / Compliance

    TRx/NRx forecast (based on IQVIA NPA data), providing key insights on physician behavior and closely linked to ex-factory output

  • Ad-hoc Analyses to Support Forecast

    Historical analog analysis

    Attribute analysis for pipeline products

    Promotional spending analysis

    SOV analysis

    Price sensitivity analysis

Impact

  • Client was able to gauge future potential of the new indication launch
  • The model further provided insights into new to market vs. switch patients, to further help in promotional messaging and targeting
  • TRx forecast provided insights into physician adoption trend to support target and segmentation revisions